With the huge increase in Internet connectivity and mobility of learning devices, learning can now become much more flexible. In this chapter, we discuss how new technologies can afford personalized learning, and in particular, how curriculum flexibility is supported by the use of technologies. We frame curriculum flexibility in terms of what, how, where, and when learning takes place. Advances in curriculum flexibility are reviewed and the elements and dimensions of a flexible curriculum addressing learner diversities are discussed. Some of the issues and challenges of flexible and distance learning are also discussed in this chapter.